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PrP (106 - 126)
KTNMKHMAGAAAAGAVVGGLG
| Overview | |
|---|---|
| Description | This peptide increases membrane microviscosity, intracellular Ca2+ concentration and cell migration in circulating leucocytes, and oxygen production in monocytes and neutrophils. It also induces apoptotic cell death and impairment of L-type voltage-sensitive calcium channel activity in the GH3 cell lines. PrP (106 €“126) stimulates leucocyte migration in a dose-dependent manner. |
| Sequence | KTNMKHMAGAAAAGAVVGGLG |
| Sequence (3 Letter) | H - Lys - Thr - Asn - Met - Lys - His - Met - Ala - Gly - Ala - Ala - Ala - Ala - Gly - Ala - Val - Val - Gly - Gly - Leu - Gly - OH |
| Molecular Weight | 1912.3 |
| Properties | |
| Purity | % Peak Area By HPLC ≥ 95% |
| Storage | -20 °C |
Ref: Diomede, L. et al. Biochem. J. 320, 563 (1996); Florio, T. et al. J. Neurosci. Res. 54, 341 (1998).
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