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γ-1-Melanocyte Stimulating Hormone (MSH), amide
| Overview | |
|---|---|
| Synonyms | γ-1-MSH, amide;γ1-MSH; g-1-MSH; g1-MSH; gamma-1-MSH; gamma1-MSHγ-1-Melanocyte Stimulating Hormone; γ1-Melanocyte Stimulating Hormone; g-1-Melanocyte Stimulating Hormone; g1-Melanocyte Stimulating Hormone; gamma-1-Melanocyte Stimulating Hormone; gamma1-Melanocyte Stimulating Hormone |
| Description | Gamma-MSH (Melanocyte Stimulating Hormone), a putative hormone in the N-terminal region of the ACTH/beta- endorphin (beta-EP) precursor protein, was studied by RIA with an antiserum against gamma 3-MSH in ACTH-producing mouse pituitary tumor cells, AtT-20/D16v. Gamma-MSH peptides have low intrinsic melanotropic activity in mammalian melanoma cells; the specific pigmentary responses appear to be affected by the structure of the C-terminal portion. |
| Sequence | {TYR}{VAL}{MET}{GLY}{HIS}{PHE}{ARG}{TRP}{ASP}{ARG}{PHE}-NH2 |
| Sequence Shortening | YVMGHFRWDRF-NH2 |
| Molecular Formula | C72H97N21O14S1 |
| C Terminal | NH2 |
| Molecular Weight | 1512.9 |
| Properties | |
| Purity | > 95% |
| Gmp Flag | 0 |
| Storage | Store the peptide at -20°C. Keep container tightly closed. |
| Note | Gamma-1-MSH is derived from ACTH 1-13. Gamma-1-MSH is a hormone that stimulates melanogenesis and facilitates learning and memory. Gamma-1-MSH can affect inflammatory and immune responses and peripheral nerve regeneration. |
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