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| Overview | |
|---|---|
| Synonyms | NKA (4-10) |
| Description | A structure-activity study of the neurokinin A (NKA) fragment NKA(4-10) was performed to investigate the importance of amino acid residues for receptor efficacy, potency and affinity at the NK2 receptor in human colon circular muscle. Two series of NKA(4-10) analogues were produced with either L-alanine or the D-enantiomer substituted. Their activities were determined in vitro by means of radioligand binding and isolated smooth muscle pharmacology. |
| Cas No | 97559-35-8 |
| Sequence | {ASP}{SER}{PHE}{VAL}{GLY}{LEU}{MET}-NH2 |
| Sequence Shortening | DSFVGLM-NH2 |
| Molecular Formula | C34H54N8O10S |
| C Terminal | NH2 |
| Molecular Weight | 766.9 |
| Properties | |
| Purity | > 95% |
| Gmp Flag | 0 |
| Storage | Store at -20°C. |
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