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| Overview | |
|---|---|
| Description | Substance P is found in the gut and in the brain. It is responsible for a number of excitatory effects on both central and peripheral neurons. Substance P contracts smooth muscle, constricts bronchioles, and increases capillary permeability. When released from afferent nerves, Substance P causes a neurogenic inflammatory response, including mast cell degranulation. It's an NK-1 agonist; a potent vasodilator and hypotensive agent; it induces salivation; it's a putative neurotransmitter in sensory (pain) afferents. |
| Cas No | 33507-63-0 |
| Sequence | {ARG}{PRO}{LYS}{PRO}{GLN}{GLN}{PHE}{PHE}{GLY}{LEU}{MET}-NH2 |
| Sequence Shortening | RPKPQQFFGLM-NH2 |
| Molecular Formula | C63H98N18O13S1 |
| C Terminal | NH2 |
| Molecular Weight | 1347.63 |
| Properties | |
| Purity | > 95% |
| Solubility | Soluble in water (1 mg/ml) |
| Gmp Flag | 0 |
| Storage | Store the peptide at -20°C. Keep container tightly closed. |
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