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Bid BH3 Peptide
| Overview | |
|---|---|
| Description | BID is a pro-apoptotic member of the "BH3-only" (BOPS) subset of the BCL-2 family of proteins that constitute a critical control point in apoptosis. Bid is the first of the BOPs reported to bind and activate Bcl-2, Bax, and Bak. Bid serves as a death-inducing ligand that moves from the cytosol to the mitochondrial membrane to inactivate Bcl-2 or to activate Bax. |
| Sequence | EDIIRNIARHLAQVGDSMDR |
| Sequence (3 Letter) | H-Glu-Asp-Ile-Ile-Arg-Asn-Ile-Ala-Arg-His-Leu-Ala-Gln-Val-Gly-Asp-Ser-Met-Asp-Arg-OH |
| Molecular Weight | 2309.6 |
| Properties | |
| Purity | > 95% By HPLC |
| Storage | Store at -20 °C, cap vial tightly at all times. |
Oh, K. J. et al J. Biol. Chem. 280, 753 (2005); Oh, K. J. et al. J. Biol. Chem. 281, 36999 (2006); Manero, F. et al. Cancer Res. 66, 2757 (2006); Zhai, D. et al. J. Biol. Chem. 280, 15815 (2005); Walensky, L. et al. Mol. Cell. 24, 199 (2006); Onuki, R. et al. Proc. Natl. Acad. Sci. U S A 99, 14716 (2002); Wang, K. Gen. Develop. 10, 2859 (1996).
About InnoPep
InnoPep Inc. is a company started by a couple of researchers with decades of expertise in peptide synthesis and conjugation aimed at enabling.