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Thrombospondin - derived Peptide; Cyclic CSVTCG
| Overview | |
|---|---|
| Description | This peptide is derived from thrombospondin and represents a binding motif responsible for thrombospondin-CD36 interaction. It is cyclized through a disulfide bond. Thrombospondin is a matrix-bound glycoprotein involved in cancer metastasis, tumor adhesion, and angiogenesis. This peptide has been shown to competitively inhibit platelet aggregation and tumor metastasis. |
| Sequence | CSVTCG (S-S Bonded) |
| Sequence (3 Letter) | H-Cys-Ser-Val-Thr-Cys-Gly-OH (S-S Bonded) |
| Molecular Weight | 566.7 |
| Properties | |
| Purity | > 95% By HPLC |
| Storage | Store at -20 °C, cap vial tightly at all times. |
Wakiyama, T. et al. Histol Histopathol 16, 345 (2001); Tsuzynski, G. et al. J Cell Biol 120, 513 (1993); Asch, A. et al. Biochem Biophys Res Commun 182, 1208 (1992).
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