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WP9QY, TNF - alpha Antagonist
| Overview | |
|---|---|
| Description | This cyclic peptide is designed to mimic the most critical tumor necrosis factor (TNF) recognition loop on TNF receptor I. It prevents interactions of TNF with its receptor. This TNF antagonist is a useful template for the development of small molecular inhibitors to prevent both inflammatory bone destruction and systemic bone loss in rheumatoid arthritis. |
| Sequence | YCWSQYLCY (Disulfide bridge: 2-8) |
| Sequence (3 Letter) | H-Tyr-Cys-Trp-Ser-Gln-Tyr-Leu-Cys-Tyr-OH (Disulfide bridge: 2-8) |
| Molecular Weight | 1226.4 |
| Properties | |
| Purity | > 95% By HPLC |
| Storage | Store at -20 °C, cap vial tightly at all times. |
Saito, H. et al. Arthritis Rheum. 56, 1164 (2007).
About InnoPep
InnoPep Inc. is a company started by a couple of researchers with decades of expertise in peptide synthesis and conjugation aimed at enabling.