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Product Code: 3118-0050

Price: $247.00

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Overview
Description

ET-1 is a potent vasoconstrictor peptide derived from endothelial cells. It plays a role in regulation of cardiovascular functions. The binding of ET-1 to G-protein coupled receptor triggers a signal transduction cascade leading to activation of the protein kinase C (PKC). PKC inhibitor potentially reverses the up regulation of ET-1. The enhanced ET-1 expression associated with the activation of PKC occurs in early diabetes.

Sequence CSCSSLMDKECVYFCHLDIIW (Disulfide bridge: 1-15 and 3-11)
Sequence (3 Letter) H - Cys - Ser - Cys - Ser - Ser - Leu - Met - Asp - Lys - Glu - Cys - Val - Tyr - Phe - Cys - His - Leu - Asp - Ile - Ile - Trp - OH (Disulfide bridge: 1 - 15 and 3 - 11)
Molecular Weight 2492
Properties
Purity % Peak Area By HPLC ≥ 95%
Storage -20 °C

Ref: Yanagisawa, M. et al. Nature. 332, 411 (1988).

About InnoPep

InnoPep Inc. is a company started by a couple of researchers with decades of expertise in peptide synthesis and conjugation aimed at enabling.

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