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Protease - Activated Receptor - 1, PAR - 1 Agonist, amide
TFLLRN - NH2
| Overview | |
|---|---|
| Description | This proteinase activated receptor (PAR-1) belongs to a subfamily of G-protein coupled receptors and is known to mediate the cellular effects of thrombin. In addition to it's varied cellular effects of thrombin, PAR-1 also has been shown to co-ordinate with PAR-4 and regulate thrombin-induced hepatocellular carcinoma harboring thrombin formation within the tumor environment classified as 'coagulation type'. |
| Sequence | TFLLRN-NH2 |
| Sequence (3 Letter) | H - Thr - Phe - Leu - Leu - Arg - Asn - NH2 |
| Molecular Weight | 761.9 |
| Properties | |
| Purity | % Peak Area By HPLC ≥ 95% |
| Storage | -20 °C |
1, Kauffmann, R. et al. Oncol. Rep. 21:1261-1267 (2009).
2, Kirilak, YA. et al. Intl. J. Mol. Med. 17:551-558 (2006).
2, Kirilak, YA. et al. Intl. J. Mol. Med. 17:551-558 (2006).
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