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C5a Receptor Agonist, mouse, human
FKP - (D - Cha) - Cha - r
| Overview | |
|---|---|
| Description | This peptide is derived from the C-terminus of the chemokine, complement fragment 5 anaphylatoxin (C5a). This peptide functions as a C5a receptor agonist. C5a is a plasma protein involved in cellular inflammatory processes by inducing chemotaxis, degranulation of leukocytes, increased vascular permeability, and cytokine production. The cyclohexylalanine at position 5 is crucial to agonist function. Arg at the last position is of the d-isomer. |
| Sequence | FKP-(D-Cha)-Cha-r |
| Sequence (3 Letter) | H - Phe - Lys - Pro - D - Cha - Cha - D - Arg - OH |
| Molecular Weight | 853.1 |
| Properties | |
| Purity | % Peak Area By HPLC ≥ 95% |
| Storage | -20 °C |
Buck, E. et al. PNAS 102, 2719 (2005); Higginbottom, A. J Biol Chem 280, 17831 (2005).
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