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IRAK - 1 (360 - 380); IRAK - 4 Peptide Substrate
KKARFSRFAGSSPSQSSMVAR
| Overview | |
|---|---|
| Description | This is a substrate peptide for Interleukin-1 Receptor-Associated Kinase (IRAK) 4, derived from the IRAK-1 activation loop peptide amino acids 360 to 380. This peptide sequence contains Ser-376, one of the primary phospho-acceptor residues of IRAK-1. IRAK-4 phosphorylates IRAK-1 as a key step in regulation of inflammatory signaling pathways. |
| Sequence | KKARFSRFAGSSPSQSSMVAR |
| Sequence (3 Letter) | H - Lys - Lys - Ala - Arg - Phe - Ser - Arg - Phe - Ala - Gly - Ser - Ser - Pro - Ser - Gln - Ser - Ser - Met - Val - Ala - Arg - OH |
| Molecular Weight | 2285.6 |
| Properties | |
| Purity | % Peak Area By HPLC ≥ 95% |
| Storage | -20 °C |
Hekmat-Nejad, M. et al. Biochem 49, 1495 (2010).
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