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390 MMP FRET Substrate IV
| Overview | |
|---|---|
| Description | This substrate is readily hydrolyzed by MMP-8, 9 and collagenase-3 (MMP-13), Abs/Em = 325/393 nm. The hydrolysis is inhibited in a 1:1 stoichiometric fashion by the tissue inhibitors of metalloproteinases, TIMP-1, TIMP-2, and TIMP-3. |
| Sequence | Mca-P-Cha-G-Nva-HA-Dap(Dnp)-NH2 |
| Sequence (3 Letter) | Mca-Pro-Cha-Gly-Nva-His-Ala-Dap(Dnp)-NH2 |
| Molecular Weight | 1100.2 |
| Properties | |
| Purity | > 95% By HPLC |
| Storage | Store at -20 °C, cap vial tightly at all times. |
Ref: Lauer-Fields, JL. and GB. Fields, Biol. Chem. 383, 1095 (2002); Lauer-Fields, JL. et al. Biochem. 40, 5795 (2001); Knauper, V. et al. J. Biol. Chem. 271, 1544 (1996).
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