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NFF - 2
| Overview | |
|---|---|
| Description | NFF-2 is hydrolyzed 60 times more rapidly by MMP-3 (kcat/Km = 59,400 s-1 M-1) than MMP-1. However, it has little discrimination between MMP-3, MMP-2 (kcat/Km = 54,000 s-1 M-1), and MMP-9 (kcat/Km = 55,300 s-1 M-1). The substrate can also be cleaved by MMP-8 and 12. Abs/Em = 325/393 nm. |
| Sequence | Mca-RPKPYA-Nva-WM-K(Dnp)-NH2 |
| Sequence (3 Letter) | Mca-Arg-Pro-Lys-Pro-Tyr-Ala-Nva-Trp-Met-Lys(Dnp)-NH2 |
| Molecular Weight | 1656.2 |
| Properties | |
| Purity | > 95% By HPLC |
| Storage | Store at -20 °C, cap vial tightly at all times. |
Ref: Bremer, C. et al. Acad. Radiol. 9 Suppl 2, S314 (2002); Nagase, H. et al. J. Biol. Chem. 269, 20952 (1994).
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