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| Overview | |
|---|---|
| Description | This is a mutated β-Amyloid 1 to 28 amino acids sequence in which the KLVFF sequence (Ab16-20) is substituted with AAVFA. The KLVFF is the shortest peptide displaying consistent high binding capacity to full-length Aβ. The first, second, and fifth residues (i.e. KLXXF) are critical for binding. The substitutions in this Aβ (1-28) amino acids sequence in the 16 to 20 region profoundly impair the ability of the peptide to aggregate and form amyloid-like fibrils. |
| Sequence | DAEFRHDSGYEVHHQAAVFAAEDVGSNK |
| Sequence (3 Letter) | H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Ala-Ala-Val-Phe-Ala-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-OH |
| Molecular Weight | 3087.2 |
| Properties | |
| Purity | > 95% By HPLC |
| Storage | Store at -20 °C, cap vial tightly at all times. |
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