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Biotin - beta - Amyloid (25 - 35)
| Overview | |
|---|---|
| Description | This peptide is amino acids 25 to 35 fragment of the ß-amyloid biotinylated at C-terminus. This peptide possesses many of the characteristics of the full-length ß-amyloid peptide, including an amphiphilic nature and an ability to aggregate, and can serve as a model system to study the conformational changes involved in Alzheimer's disease. Aggregates of ß-amyloid (25 €“35) have been shown to possess the neurotrophic and neurotoxic properties of their full-length counterparts and there is evidence that the monomeric form of the peptide may itself be cytotoxic. |
| Sequence | Biotin-GSNKGAIIGLM |
| Sequence (3 Letter) | Biotin-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-OH |
| Molecular Weight | 1286.6 |
| Properties | |
| Purity | > 95% By HPLC |
| Storage | Store at -20 °C, cap vial tightly at all times. |
Wei, G. and J. Shea Biophys. J. 91, 1638 (2006).
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