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Glutamate Receptor Endocytosis Inhibitor
| Overview | |
|---|---|
| Description | This GluR2<Sub>3Y peptide was used in ELISA cell-surface assay for the insulin-stimulated endocytosis of native AMPA receptors in cultured hippocampal neurons. GluR23Y prevented any insulin-induced reduction. The blockade of insulin action was observed when the GluR2<Sub>3Y peptide was delivered into neurons by fusing it to the membrane transduction domain of HIV-1. |
| Sequence | YKEGYNVYG |
| Sequence (3 Letter) | H-Tyr-Lys-Glu-Gly-Tyr-Asn-Val-Tyr-Gly-OH |
| Molecular Weight | 1092.2 |
| Properties | |
| Purity | > 95% By HPLC |
| Storage | Store at -20 °C, cap vial tightly at all times. |
Ahmadian, G. et al. EMBO J. 23, 1040 (2004), Wang, D. et al. J. Biol. Chem. 279, 41267 (2004).
About InnoPep
InnoPep Inc. is a company started by a couple of researchers with decades of expertise in peptide synthesis and conjugation aimed at enabling.