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MOG (101 - 120), human, mouse
| Overview | |
|---|---|
| Description | This is amino acids 101 to 120 fragment of myelin oligodendrocyte glycoprotein (MOG), one of the major MOG B-cell epitopes in transgenic mice. MOG is a potential target antigen of the central nervous system known to induce autoreactive T cell response and demyelinating anti-MOG antibodies in multiple sclerosis (MS) patients. Studies demonstrated that a quantitatively minor myelin protein, MOG, is also strongly encephalogenic in mice, rats, marmosets, and rhesus monkeys, which is highly relevant to MS. |
| Sequence | RDHSYQEEAAMELKVEDPFY |
| Sequence (3 Letter) | H-Arg-Asp-His-Ser-Tyr-Gln-Glu-Glu-Ala-Ala-Met-Glu-Leu-Lys-Val-Glu-Asp-Pro-Phe-Tyr-OH |
| Molecular Weight | 2457.7 |
| Properties | |
| Purity | > 95% By HPLC |
| Storage | Store at -20 °C, cap vial tightly at all times. |
Khare, M. et al. Int. Immunol. 15, 535 (2003).
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