![[Arg(Me2a)2, pThr3] - Histone H3 (1 - 21) - GGK(Biotin)](/media/com_eshop/products/resized/prod_150x150-500x500.png "[Arg(Me2a)2, pThr3] - Histone H3 (1 - 21) - GGK(Biotin)")
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[Arg(Me2a)2, pThr3] - Histone H3 (1 - 21) - GGK(Biotin)
| Overview | |
|---|---|
| Description | This peptide is histone H3 (1-21) with asymmetrical dimethylation at Arg2 and phosphorylation at Thr3, followed by a C-terminal GGK with biotinylation on the side chain of Lys. Asymmetrical dimethylation at Arg2 inhibits Lys 4 methylation and is associated with silenced chromatin. Phosphorylation of Thr3 begins in mitotic prophase and reverses in anaphase. This process is carried out by haspin in vitro. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form. |
| Sequence | A-R(Me2a)-pT-KQTARKSTGGKAPRKQLAGG-K(Biotin) |
| Sequence (3 Letter) | H-Ala-Arg(Me2a)-pThr-Lys-Gln-Thr-Ala-Arg-Lys-Ser-Thr-Gly-Gly-Lys-Ala-Pro-Arg-Lys-Gln-Leu-Ala-Gly-Gly-Lys(Biotin)-OH |
| Molecular Weight | 2831.2 |
| Properties | |
| Purity | > 95% By HPLC |
| Storage | Store at -20 °C, cap vial tightly at all times. |
Klose, R. and Y. Zhang.Nat Struct Mol Biol 14, 1058 (2007); Dai, J. et al. Gene Dev 19, 472 (2005).
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