![[Arg(Me2s)2, Lys(Me3)4] - Histone H3 (1 - 21) - GGK(Biotin)](/media/com_eshop/products/resized/prod_150x150-500x500.png "[Arg(Me2s)2, Lys(Me3)4] - Histone H3 (1 - 21) - GGK(Biotin)")
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[Arg(Me2s)2, Lys(Me3)4] - Histone H3 (1 - 21) - GGK(Biotin)
| Overview | |
|---|---|
| Description | This peptide is histone H3 (1-21) with symmetrical dimethylation at Arg2 and trimethylation at Lys4, followed by a C-terminal GGK with biotinylation on the side chain of Lys. Dimethylation of the guanidinium group of Arg2 is associated with transcriptional silencing. Trimethylation of Lys4, which is catalyzed by Set1, is associated exclusively with active euchromatic genes. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form. |
| Sequence | A-R(Me2s)-T-K(Me3)-QTARKSTGGKAPRKQLAGG-K(Biotin) |
| Sequence (3 Letter) | H-Ala-Arg(Me2s)-Thr-Lys(Me3)-Gln-Thr-Ala-Arg-Lys-Ser-Thr-Gly-Gly-Lys-Ala-Pro-Arg-Lys-Gln-Leu-Ala-Gly-Gly-Lys(Biotin)-OH |
| Molecular Weight | 2793.2 |
| Properties | |
| Purity | > 95% By HPLC |
| Storage | Store at -20 °C, cap vial tightly at all times. |
Musselman, CA and TG. Kutateladze Mol Interv 9, 314 (2010); Kirmizis, A. et al. Nat Struct Mol Biol 16, 449 (2009); Tamaru, H. et al. Nat Genet 34, 75 (2003); Santos-Rosa, H. et al. Nature 419, 407 (2002).
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InnoPep Inc. is a company started by a couple of researchers with decades of expertise in peptide synthesis and conjugation aimed at enabling.