![[Cit2, pThr3] - Histone H3 (1 - 21) - GGK(Biotin)](/media/com_eshop/products/resized/prod_150x150-500x500.png "[Cit2, pThr3] - Histone H3 (1 - 21) - GGK(Biotin)")
Call Now: +1 858 800 3101 Email: info@innopep.com
Shopping Cart
0 Item(s) - $0.00
Your shopping cart is empty!
[Cit2, pThr3] - Histone H3 (1 - 21) - GGK(Biotin)
| Overview | |
|---|---|
| Description | This peptide is histone H3 (1-21) with deimination at Arg2 and phosphorylation at Thr3 followed by a C-terminal GGK linker with biotinylation on the side chain of this Lys. Arg2 is deiminated by peptidyl arginine deiminase 4 (PADI4). Conversion to citrulline (Cit) blocks methylation at this site and inhibits transcriptional activation. Phosphorylation of Thr3 begins in mitotic prophase and reverses in anaphase. This process is carried out by haspin in vitro. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form. |
| Sequence | A-Cit-pT-KQTARKSTGGKAPRKQLAGG-K(Biotin) |
| Sequence (3 Letter) | H-Ala-Cit-pThr-Lys-Gln-Thr-Ala-Arg-Lys-Ser-Thr-Gly-Gly-Lys-Ala-Pro-Arg-Lys-Gln-Leu-Ala-Gly-Gly-Lys(Biotin)-OH |
| Molecular Weight | 2804.2 |
| Properties | |
| Purity | > 95% By HPLC |
| Storage | Store at -20 °C, cap vial tightly at all times. |
Dai, J. et al. Gene Dev 19, 472 (2005); Cuthbert, G. et al. Cell 118, 545 (2004).
About InnoPep
InnoPep Inc. is a company started by a couple of researchers with decades of expertise in peptide synthesis and conjugation aimed at enabling.