![[Lys(Ac)8] - Histone H4 (1 - 21) - GGK(Biotin), H4K8(Ac), biotin - labeled](/media/com_eshop/products/resized/prod_150x150-500x500.png "[Lys(Ac)8] - Histone H4 (1 - 21) - GGK(Biotin), H4K8(Ac), biotin - labeled")
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[Lys(Ac)8] - Histone H4 (1 - 21) - GGK(Biotin), H4K8(Ac), biotin - labeled
| Overview | |
|---|---|
| Description | This peptide is histone H4, amino acids 1 to 21. It is acetylated at Lys-8 and at the N-terminus with a C-terminus GG linker, followed by a biotinylated lysine. The acetylation of histone H4 causes structural changes that amplify the binding of transcription factors to their recognition sites within the nucleosome. |
| Sequence | Ac-SGRGKGG-K(Ac)-GLGKGGAKRHRKV-GGK(Biotin) |
| Sequence (3 Letter) | H-Ala-Arg(Me1)-Thr-Lys-Gln-Thr-Ala-Arg-Lys-Ser-Thr-Gly-Gly-Lys-Ala-Pro-Arg-Lys-Gln-Leu-Ala-Gly-Gly-Lys(Biotin)-NH2 |
| Molecular Weight | 2644.1 |
| Properties | |
| Purity | > 95% By HPLC |
| Storage | Store at -20 °C, cap vial tightly at all times. |
Vettes-Dadey, M. et al. EMBO J 15, 10 (1996).
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