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Myristoylated ADP - Ribosylation Factor 6, myr - ARF6 (2 - 13)
| Overview | |
|---|---|
| Description | Members of the ARF family are subjected to myristoylation at the N-terminal glycine residue, a lipid co-translational modification that appears essential for functional activity. This myristoylated ARF-6 is a strong inhibitor of calcium-evoked catecholamine secretion and phospholipase D activation in chromaffin cells, the non-myristoylated ARF-6 (cat# 60782) and the myristolated ARF-1 (cat# 60781) have mimimal effects. |
| Sequence | Myr-GKVLSKIFGNKE |
| Sequence (3 Letter) | Myr-Gly-Lys-Val-Leu-Ser-Lys-Ile-Phe-Gly-Asn-Lys-Glu-OH |
| Molecular Weight | 1531 |
| Properties | |
| Purity | > 95% By HPLC |
| Storage | Store at -20 °C, cap vial tightly at all times. |
Ref: Galas, M-C. et al. J. Biol. Chem. 272, 2788 (1997); Donaldson, JG. and RD. Klausner, Curr. Opin. Cell Biol. 6, 527 (1994); Matsukawa, J. et al. J. Biol. Chem. 278, 36470 (2003).
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