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p53 (17 - 26)
ETFSDLWKLL
| Overview | |
|---|---|
| Description | This peptide is amino acids 17 to 26 fragment of p53, the Mdm-2 binding domain of p53 known also as p53N. This sequence contains all of the residues that contact the binding domain of Mdm-2. The tumor suppressor protein p53 is important in maintaining genome stability and in preventing cancer development. |
| Sequence | ETFSDLWKLL |
| Sequence (3 Letter) | H - Glu - Thr - Phe - Ser - Asp - Leu - Trp - Lys - Leu - Leu - OH |
| Molecular Weight | 1251.5 |
| Properties | |
| Purity | % Peak Area By HPLC ≥ 95% |
| Storage | -20 °C |
Wang, Y. et al. J. Biol. Chem. 281, 24803 (2006), Kanovsky, M. et al. PNAS 98, 12438 (2001).
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