![[Lys(Ac)<sup>40</sup>] - Ac - a - Tubulin (29 - 50) - WGK(Biotin); TubK40(Ac) - WGK, biotin - labeled<br>Ac - GIQPDGQMPSD - K(ac) - TIGGGDDSFNWG - K(biotin)](/media/com_eshop/products/resized/prod_150x150-500x500.png "[Lys(Ac)<sup>40</sup>] - Ac - a - Tubulin (29 - 50) - WGK(Biotin); TubK40(Ac) - WGK, biotin - labeled<br>Ac - GIQPDGQMPSD - K(ac) - TIGGGDDSFNWG - K(biotin)")
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[Lys(Ac)40] - Ac - a - Tubulin (29 - 50) - WGK(Biotin); TubK40(Ac) - WGK, biotin - labeled
Ac - GIQPDGQMPSD - K(ac) - TIGGGDDSFNWG - K(biotin)
| Overview | |
|---|---|
| Description | This is an acetylated alpha tubulin peptide at lysine 40 with a C-terminal WG linker followed by a biotinylated lysine. The acetylation at lysine 40 of this peptide is shown to have a therapeutic interest in diseases involving altered intracellular transport such as Huntington's disease. Histone Deacetylase (HDAC) inhibitors have been shown to increase vesicular transport of brain derived neurotrophic factor thereby increasing acetylation of tubulin at lysine 40. |
| Sequence | Ac-GIQPDGQMPSD-K(ac)-TIGGGDDSFNWG-K(biotin) |
| Sequence (3 Letter) | Ac - Gly - Ile - Gln - Pro - Asp - Gly - Gln - Met - Pro - Ser - Asp - - Lys(ac) - Thr - Ile - Gly - Gly - Gly - Asp - Asp - Ser - Phe - Asn - Trp - Gly - Lys(biotin) |
| Molecular Weight | 2918.2 |
| Properties | |
| Purity | % Peak Area By HPLC ≥ 95% |
| Storage | -20 °C |
Dompierre JP. et al. J Neurosci 27(13):3571-3583 (2007).
About InnoPep
InnoPep Inc. is a company started by a couple of researchers with decades of expertise in peptide synthesis and conjugation aimed at enabling.