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Endothelin 1, human, porcine
| Overview | |
|---|---|
| Synonyms | ET-1 |
| Description | This peptide is a potent vasoconstrictor, derived from endothelial cells. Potent agonist for ETA and ETB endothelin receptors. Induces the production of hypoxia-inducible factor 1α, and, thus, the production of VEGF. |
| Cas No | 117399-94-7 |
| Sequence | {CYS}{SER}{CYS}{SER}{SER}{LEU}{MET}{ASP}{LYS}{GLU}{CYS}{VAL}{TYR}{PHE}{CYS}{HIS}{LEU}{ASP}{ILE}{ILE}{TRP} |
| Sequence Shortening | CSCSSLMDKECVYFCHLDIIW |
| Molecular Formula | C109H159N25O32S5 |
| Disulfide Bridge | Disulfide bridges: 1-15 and 3-11 |
| Molecular Weight | 2491.9 |
| Properties | |
| Purity | > 95% |
| Format Bridge | 1-15,3-11 |
| Solubility | The peptide is soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents. |
| Storage | Store the peptide at -20°C. Keep container tightly closed. Store in a cool dry place. |
| Note | Potent vasoconstrictor peptide |
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