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TAT
| Overview | |
|---|---|
| Description | TaT is a transcriptional transactivator protein that binds to a regulatory element in the HIV-1 long terminal repeat. By recruiting P-TEFb to TAR, TaT promotes transcription of viral mRNA. This arginine-rich TAT peptide penetrates plasma membrane directly, but not through endocytosis. TaT has similar immunosuppressive effects as transforming growth factor-beta (TGF beta) and both inhibit lymphocyte proliferation. |
| Sequence | {TYR}{GLY}{ARG}{LYS}{LYS}{ARG}{ARG}{GLN}{ARG}{ARG}{ARG}-NH2 |
| Sequence Shortening | YGRKKRRQRRR-NH2 |
| Molecular Formula | C64H119N33O13 |
| C Terminal | NH2 |
| Molecular Weight | 1558.85 |
| Properties | |
| Purity | > 95% |
| Gmp Flag | 0 |
| Storage | Store at -20°C. Keep tightly closed. Store in a cool dry place. |
About InnoPep
InnoPep Inc. is a company started by a couple of researchers with decades of expertise in peptide synthesis and conjugation aimed at enabling.