![[Gln8]-C517 (LH-RH), chicken](/media/com_eshop/products/resized/prod_150x150-500x500.png "[Gln8]-C517 (LH-RH), chicken")
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[Gln8]-C517 (LH-RH), chicken
| Overview | |
|---|---|
| Synonyms | [Gln8]-Luteinizing hormone releasing hormone |
| Description | [Gln8] Luteinizing hormone releasing hormone ([Gln8] LH-RH), Avian hypothalamic peptide that stimulates release of gonadotropins from anterior pituitary, thus regulating reproductive functions. It has been assumed, usually with good reason, that D-amino acids with large aromatic side-chains must be present in position 6 of both LH-RH superagonists and antagonists for the highest levels of biological activity to be reached. However, using one of a recent generation of potent lH-RH inhibitory analogs as a model, we have found that the insertion of D-lysine or, better still, D-arginine in this position results in greater antiovulatory activity in the rat over corresponding D-phenylalanine6- and D-tryptophan6-analogs. |
| Cas No | 47922-48-5 |
| Sequence | {pGLU}{HIS}{TRP}{SER}{TYR}{GLY}{LEU}{GLN}{PRO}{GLY} |
| Molecular Formula | C54H71N15O14 |
| C Terminal | NH2 |
| Molecular Weight | 1154.23 |
| Properties | |
| Purity | > 95% |
| Gmp Flag | 0 |
| Storage | Store at -20°C. |
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