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| Overview | |
|---|---|
| Synonyms | LH-RH, salmonLuteinizing hormone releasing hormone, salmon |
| Description | LH-RH is a hypothalamic peptide that stimulates release of gonadotrophins from anterior pituitary, thus regulating reproductive functions. It has been assumed, usually with good reason, that D-amino acids with large aromatic side-chains must be present in position 6 of both LH-RH superagonists and antagonists for the highest levels of biological activity to be reached. However, using one of a recent generation of potent lH-RH inhibitory analogs as a model, we have found that the insertion of D-lysine or, better still, D-arginine in this position results in greater antiovulatory activity in the rat over corresponding D-phenylalanine6- and D-tryptophan6-analogs. |
| Cas No | 86073-88-3 |
| Sequence | {pGLU}{HIS}{TRP}{SER}{TYR}{GLY}{TRP}{LEU}{PRO}{GLY} |
| Molecular Formula | C60H73N15O13 |
| C Terminal | NH2 |
| Molecular Weight | 1212.31 |
| Properties | |
| Purity | > 95% |
| Gmp Flag | 0 |
| Storage | Store at -20°C. |
InnoPep Inc. is a company started by a couple of researchers with decades of expertise in peptide synthesis and conjugation aimed at enabling.