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Bid BH3 - R8

Product Code: 1264-005

Price: $151.00

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Overview
Description Bid BH3 is a pro-apoptotic member of the "BH3-only" subset of BCL-2 family proteins that constitute a critical control point in apoptosis. BID BH3 interacts with Bax to induce mitochondrial outer membrane permeabilization in the apoptotic process. This peptide contains 8 Arg residues in the L-isomeric form on the N-terminus. BID Tagging with poly-arginine facilitates cell internalization. R8BIDH3 has been shown to induce apoptosis of Jurkat leukemia cells in vitro.
Sequence RRRRRRRRGEDIIRNIARHLAQVGDSMDR
Sequence (3 Letter) H-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Gly-Glu-Asp-Ile-Ile-Arg-Asn-Ile-Ala-Arg-His-Leu-Ala-Gln-Val-Gly-Asp-Ser-Met-Asp-Arg-OH
Molecular Weight 3616.2
Properties
Purity > 95% By HPLC
Storage Store at -20 °C, cap vial tightly at all times.
Letai, A. J Clin Invest 115, 2648 (2005). Goldsmith, K. et al. Proc Amer Assoc Cancer Res 45,1829 (2004). Goldsmith, K. et al. Oncogene 25, 4525 (2006).

About InnoPep

InnoPep Inc. is a company started by a couple of researchers with decades of expertise in peptide synthesis and conjugation aimed at enabling.

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