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Pro - apoptotic Peptide, klaklakklaklak, 5 - FAM - labeled
| Overview | |
|---|---|
| Description | This is the pro-apoptotic peptide composed of D-amino acids, 5-FAM labeled. This alpha-helical amphipathic peptide is toxic to eukaryotic cells if internalized by a suitable targeting mechanism. It disrupts mitochondrial membranes upon receptor-mediated cell internalization and causes programmed cell death. |
| Sequence | 5-FAM-klaklakklaklak-NH2 |
| Sequence (3 Letter) | 5-FAM-D-Lys-D-Leu-D-Ala-D-Lys-D-Leu-D-Ala-D-Lys-D-Lys-D-Leu-D-Ala-D-Lys-D-Leu-D-Ala-D-Lys-NH2 |
| Molecular Weight | 1881.3 |
| Properties | |
| Purity | > 95% By HPLC |
| Storage | Store at -20 °C, cap vial tightly at all times. |
Marks, A. et al. Cancer Res. 65, 2373 (2005); Kolonin, M. et al. Nat. Med. 10, 625 (2004).
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