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PUMA BH3

Product Code: 1256-005

Price: $132.00

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Overview
Description This is a PUMA (p53 upregulated modulator of apoptosis) BH3 domain peptide. PUMA together with Bcl-xL, and cytoplasmic p53 coordinates p53 functions. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome C release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis.
Sequence EEQWAREIGAQLRRMADDLNAQYER
Sequence (3 Letter) H-Glu-Glu-Gln-Trp-Ala-Arg-Glu-Ile-Gly-Ala-Gln-Leu-Arg-Arg-Met-Ala-Asp-Asp-Leu-Asn-Ala-Gln-Tyr-Glu-Arg-OH
Molecular Weight 3049.3
Properties
Purity > 95% By HPLC
Storage Store at -20 °C, cap vial tightly at all times.
Chipuk, J. et al. Science 309, 1732 (2005), Nakano, K. et al. Mol. Cell 7, 683 (2001), Yu, J. et al. Mol. Cell 7, 673 (2001), Han, J. et al. Proc. Natl. Acad. Sci. U S A. 98, 11318 (2001).

About InnoPep

InnoPep Inc. is a company started by a couple of researchers with decades of expertise in peptide synthesis and conjugation aimed at enabling.

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