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TRP - 2 (180 - 188)
| Overview | |
|---|---|
| Description | This peptide is derived from tyrosinase-related protein 2 (TRP2) residues 180-188. TRP2 belongs to the melanocyte differentiation antigens and has been implicated as a target for immunotherapy of human as well as murine melanoma. Studies show that this TRP2 derived peptide can bind to mouse and human MHC class I molecules. Immunization with TRP2 peptide loaded dendritic cells (DCs) results in effective induction of antitumor immunity. |
| Sequence | SVYDFFVWL |
| Sequence (3 Letter) | H-Ser-Val-Tyr-Asp-Phe-Phe-Val-Trp-Leu-OH |
| Molecular Weight | 1175.4 |
| Properties | |
| Purity | > 95% By HPLC |
| Storage | Store at -20 °C, cap vial tightly at all times. |
Park, J. et al. The EMBO J. 18, 3024 (1999); Bichsel, S. et al. J. Biol. Chem. 279, 35228 (2004)
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