Call Now: +1 858 800 3101 Email: info@innopep.com


Your shopping cart is empty!

InnoPep Products Filter

InnoPep Caspase 8 Substrate 1f, fluorogenic
Ac - IETD - AFC
Ac-IETD-AFC.. Product #: 3041-0500 Regular price: $159.00 $159.00

Caspase 8 Substrate 1f, fluorogenic
Ac - IETD - AFC

Product Code: 3041-0500
Weight: 5.00mg

Price: $159.00

Available Options

* Package Size:

AFC (7-amino-4-trifluoromethylcoumarin)-derived caspase substrates are widely used for the fluorimetric detection of various caspase activities. Cleavage of AFC peptides by caspases generate strongly fluorescent AFC that is monitored fluorimetrically at 500-510 nm with excitation of 370-390 nm.Caspase-8 substrate

Gurtu V, et al. (1997). Fluorometric and colorimetric detection of caspase activity associated with apoptosis. Anal Biochem 251, 98-102; Martins LM, et al. (1997). Activation of multiple interleukin-1beta converting enzyme homologues in cytosol and nuclei of HL-60 cells during etoposide-induced apoptosis. J Biol Chem 272, 7421-30; Deveraux QL, et al. (1997). X-linked IAP is a direct inhibitor of cell-death proteases. Nature 388, 300-4; Xiang J, et al. (1996). BAX-induced cell death may not require interleukin 1 ?-converting enzyme-like proteases. Proc Natl Acad Sci USA 93, 14559-63.
Chemistry
Purity % Peak Area By HPLC ≥ 95%
Molecular Weight 729.6
Sequence Ac-IETD-AFC
Sequence (3 Letter) Ac - Ile - Glu - Thr - Asp - AFC
Biology
Storage -20°C desiccated and protected from light

About InnoPep

InnoPep Inc. is a company started by a couple of researchers with decades of expertise in peptide synthesis and conjugation aimed at enabling.

Newsletter Signup

Stay Updated With Our Latest Products.

Your email is safe with us, we don't spam.