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Adeno - Associated Virus Epitope 2 (AAV2)
VPQYGYLTL
| Overview | |
|---|---|
| Description | This peptide is the capsid derived immunodominant adeno-associated virus 2 (AAV2), CD8 T cell epitope. Liver toxicity observed in a clinical trial of AAV2 delivered systemically to patients with hemophilia was ascribed to killing of vector-transduced hepatocytes by capsid-specific T-cells. |
| Sequence | VPQYGYLTL |
| Sequence (3 Letter) | H - Val - Pro - Gln - Tyr - Gly - Tyr - Leu - Thr - Leu - OH |
| Molecular Weight | 1053.2 |
| Properties | |
| Purity | % Peak Area By HPLC ≥ 95% |
| Storage | -20 °C |
Murphy, S. et al. Blood (ASH Annual Meeting Abstracts), 108 (2006), Mingozzi, F. et al. Nature Medicine 10.1038/nm1549 (2007), Wang, L. et al. Therapy. 18, 185 (2007).
About InnoPep
InnoPep Inc. is a company started by a couple of researchers with decades of expertise in peptide synthesis and conjugation aimed at enabling.